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Saturday, December 16, 2017

Unsynchronized Brain Waves During Sleep Make Us Forget


Likened to a tennis serve where the ball toss and the racket swing must coordinate
perfectly to score an ace, overnight brain waves must sync properly for remembering
to occur, a new study finds.  As with everything, it’s all about timing.  While slow
and fast brain waves are integrated and balanced in younger adults, when we age
slow waves that occur during non-rapid eye movement (NREM) sleep fail to fully
coordinate with quick electrical bursts known as spindles.

Using tennis terminology, the slow waves are like the toss of the ball, while the fast
waves are like the swing of the racket. If either of these two components are off in
terms of rhythm, the serve will either travel short or long in terms of distance, or go
out of bounds or the racket might even fail to make contact with the ball completely.
In sleep, this mistiming prevents older adults from being able to save new memories.  
These findings explain way older adults often seem able to better remember things
that occurred in the past rather than those that recently occurred.  The study also
suggests that this problem is the result of atrophy of the medial frontal cortex, an
area in the brain responsible for deep sleep which is restorative.  

The good news from this study is that there is now hope for a potential treatment
that could help with memory loss in aging adults.  New studies are being undertaken
to examine the effects of applying electrical stimulation to the frontal lobe of the
brain in an effort to synchronize slow waves with spindles   According to the studies
senior author Matthew Walker, “By electrically boosting these nighttime brainwaves,
we hope to restore some degree of healthy deep sleep in the elderly and those with
dementia, and in doing so, salvage aspects of their learning and memory,"

Source

Helfrich, R. F., Mander, B. A., Jagust, W. J., Knight, R. T. & Walker, M. P. (2017). Old Brains Come Uncoupled in Sleep:  Slow Wave - Spindle Synchrony, Brain Atrophy and Forgetting.. Neuron.  





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